Scientists were able to detect genetic changes that may significantly increase the risk of developing anorexia. To such conclusions the new study, which was the largest of its kind. It should be noted that these changes include both small and
differences between the DNA of healthy and sick man, and quite
substantial.
Thus, despite the magnitude of the research, scientists still are planning to hold several similar studies involving an even greater number of people to finally confirm the results.
"When we discover a rather large number of genes that are in some way associated with the development of the disease, we are now much easier to develop specific diagnostic markers to identify those people who are at risk," - says the expert study, Dr. Hakon Hakonarson (Hakon Hakonarson) engaged in scientific work in a specialized center at Children's Hospital of Philadelphia.
People suffering from anorexia nervosa have panic overweight, among other things have greatly distorted perception of their own body. 10 times stronger than the influence of this disease affects women.
Studies on twins have shown that anorexia - is largely a hereditary disease, since the presence of the corresponding genes in most cases - it is more than 50 percent probability that a person is predisposed to the disease. Nevertheless, all the same in spite of the discovered relationship between the development of the disease and gene disorders, yet the mechanism of the genetic underpinnings of anorexia is remains unknown.
In order to still closer to unraveling the mystery, Hakonarson and his colleagues examined the genomes of 1003 people suffering from anorexia, the average age was 27 years, and compared them with the genomes of 3,733 healthy children, whose average age was 13 years. Of course, some concern about the possible future development of anorexia existed, but the probability was so low that it is unlikely it could affect the results.
As a result, researchers have found several injuries along the genome, so-called single nucleotide polymorphisms, which can serve as a genetic basis for the development of anorexia. These lesions are also present in the human genome with this disease, such as autism. Although it is absolutely two different diseases, disorders, occurring in the body, it is very similar. Experts extremely intrigued by the coincidence detection and plan further studies to do a thorough study of the issue.
Experts make bold assumptions about the possible conclusions to which they can come as a result of the forthcoming investigations, but whether they will be credible, we will know soon.
Thus, despite the magnitude of the research, scientists still are planning to hold several similar studies involving an even greater number of people to finally confirm the results.
"When we discover a rather large number of genes that are in some way associated with the development of the disease, we are now much easier to develop specific diagnostic markers to identify those people who are at risk," - says the expert study, Dr. Hakon Hakonarson (Hakon Hakonarson) engaged in scientific work in a specialized center at Children's Hospital of Philadelphia.
People suffering from anorexia nervosa have panic overweight, among other things have greatly distorted perception of their own body. 10 times stronger than the influence of this disease affects women.
Studies on twins have shown that anorexia - is largely a hereditary disease, since the presence of the corresponding genes in most cases - it is more than 50 percent probability that a person is predisposed to the disease. Nevertheless, all the same in spite of the discovered relationship between the development of the disease and gene disorders, yet the mechanism of the genetic underpinnings of anorexia is remains unknown.
In order to still closer to unraveling the mystery, Hakonarson and his colleagues examined the genomes of 1003 people suffering from anorexia, the average age was 27 years, and compared them with the genomes of 3,733 healthy children, whose average age was 13 years. Of course, some concern about the possible future development of anorexia existed, but the probability was so low that it is unlikely it could affect the results.
As a result, researchers have found several injuries along the genome, so-called single nucleotide polymorphisms, which can serve as a genetic basis for the development of anorexia. These lesions are also present in the human genome with this disease, such as autism. Although it is absolutely two different diseases, disorders, occurring in the body, it is very similar. Experts extremely intrigued by the coincidence detection and plan further studies to do a thorough study of the issue.
Experts make bold assumptions about the possible conclusions to which they can come as a result of the forthcoming investigations, but whether they will be credible, we will know soon.
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