What is the Correct Method for Using Nitroglycerin Ointment?

What is the Correct Method for Using Nitroglycerin Ointment?

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QUESTION: I have been a sufferer of angina pectoris for several years.
Recently, for the first time my doctor prescribed an ointment of nitroglycerin
to use for my condition. When I decided to spread it carefully over my heart
where it would do the most good, my wife wanted to put it all over my chest,
like some cold medicine. Which is the correct method?
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ANSWER: Nitroglycerin absorbed though the skin uses a route of administration
called "transdermal" rather than "oral" or "intravenous", and can afford you
its benefits for a longer period of time than the "under the tongue" pills or
capsules. In order for it to be absorbed correctly, you must cover an area of
skin that is sufficiently large to do the job, about 6 inches long by 3-6
inches wide. It doesn't necessarily have to be placed over your heart, for
any place on the chest will work just as well. You might even use the upper
portion of your arm or back (but stay away from skin that is too hairy). The
ointment will begin to take effect in about 30 minutes and the effects
continue for from six to eight hours. Use the wax paper that comes with the
tube, as it usually has markings that will indicate to you the size of the
area that should be covered. Then attach the wax paper to your skin with
adhesive tape. Try not to get the medication on your fingers since it can be
absorbed from there too, and increase or cause side effects. When you are
ready for the next application, remove the wax paper, wash the skin carefully,
and then apply the next dose to another site on your chest. This will help to
avoid possible skin rashes that can be caused by both the ointment and the
tape. To keep peace in the family you can alternate sites between your heart
area and anywhere else on your chest your wife wishes to place this effective
and important medication for your condition.